Absorption from daily dietary equivalents of vitamin B12 by patients with anemia was significant, but was not nutritionally adequate. Increasing the amount of either vitam- in B12 or exogenous intrinsic factor (IF) ingested by these patients increased – Vitamin B12 absorption tion. To absorb 1 µg from a 20-µ g dose of vitamin B12, the patients needed enough IF to bind 5 to 10 µ gof vitamin B12. Hog IF was found to mediate absorption from physiological doses of vitamin B12 as efficiently as human IF.
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© 1972 S. Karger AG, Basel
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