In vitro labelling of circulating blasts with 3H-thymidine was followed by their autotransfusion in a case of steady state acute lymphoblastic leukaemia. Labelling index and mean grain values were then determined autoradiographically at various intervals on both peripheral and marrow blood.The results showed that circulating blasts in S-phase returned to the marrow and then passed back to the circulating compartment after division. Their half-live values was 22.1 h.
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© 1972 S. Karger AG, Basel
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