The possibility of direct release of immunoglobulin from the erythrocyte surfaces due to the break of the erythrocyte-immunoglobulin binding after the i.v. administration of L-asparaginase has been shown in patients with acquired hemolytic anemia of IgG and IgA type. These studies were carried out by means of immunofluorescent observation, the determination ofthe immunoglobulin content in the serum, and the direct antiglobulin test.
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© 1972 S. Karger AG, Basel
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