We report a case of a 39-year-old man with λ-light-chain multiple myeloma, nephrotic syndrome due to λ-light-chain deposition disease in kidneys and amyloidosis in other tissues. The patient was treated with melphalan and prednisone for 1 year. After that, he was administered interferon-α2b (IFN-α2b; 3 MU, 3 times a week) as maintenance therapy for 2 years. At present, 5 years and 6 months after the initial diagnosis, the patient receives IFN-α2b (3 MU, twice a week) and remains in complete haematological remission.

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