... brings challenges, particularly when facing cytological limitedly sized samples. To overcome these challenges, multiplex immunocytochemistry (mICC) techniques offer the simultaneous detection of multiple markers from a single section. These advances complement the highly complex imaging techniques...

.... These samples are often the only available material for accurate diagnosis and for performing ancillary studies, such as immunocytochemistry (ICC) or the detection of molecular biomarkers. Summary: While the use of immunohistochemistry is well established and standardized on formalin-fixed-paraffin-embedded...

... diagnostic techniques have been applied, including immunocytochemistry (ICC). This review discusses the application and evaluation of ICC in thyroid fine needle aspiration. Summary: Currently, three immunostaining preparation methods are available for cytological materials: liquid-based cytology, cell block...

... conditions for the control and patient samples. Our aim was to develop a procedure for preparing integrated on-slide positive controls for immunocytochemistry (ICC) on methanol-fixed cytospins. Methods: Leftover diagnostic cytology samples with sufficient cells and confirmed expression of Calretinin, MOC31...

...Irena Srebotnik Kirbis Background: Immunocytochemistry (ICC) is a widely available and extensively used ancillary method in diagnostic cytopathology with great variability in all test phases and a low level of adequate quality management. The non-standardized ICC landscape is now challenged...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 High-grade urothelial carcinoma Immunocytochemistry Urine cytology p53 Vimentin Urine cytology is widely used for the screening and follow-up of urothelial carcinoma...

... has not yet been evaluated. In this report, the cytological findings and GRM1 immunocytochemistry of two cases of CMF are described. Case Presentations: Case 1 was a 15-year-old girl with a rib tumor. Imaging findings suggested a benign neurogenic tumor such as schwannoma. The tumor had increased...

... to reduce atypical cases and improve diagnostic accuracy by investigating the utility of cell block (CB) analysis. Methods: FNAB CB samples (2018–2022) were reviewed using smear only or CBs. CB-based diagnosis was performed with 2D morphological analysis and immunocytochemistry using ER, CK5/6, p63, SMA...

...Nanako Sakabe; Sayumi Maruyama; Chihiro Ito; Yuka Shimoyama; Tetsuya Komene; Wataru Oboshi; Shouichi Sato; Kazuhisa Sudo; Katsuhide Ikeda Introduction: Liquid-based cytology (LBC)-fixed samples can be used for preparing multiple specimens of the same quality and for immunocytochemistry (ICC...

..., methods, instructions or products referred to in the content or advertisements. Podocyte Liquid-based cytology Immunocytochemistry Urine cytology Glomerular disease Podocytes are highly specialized epithelial cells that play an important role as filters that prevent the leakage of high...

... studies of SCLC revealed the potential rise of new predictive and prognostic biomarkers that, whenever validated by immunocytochemistry, may potentially assist to tailor the best therapy, including immune checkpoint inhibition. mauro.papotti@unito.it 2 09 2021 14 09 2021 16 11 2021...

...) method for overall cellularity, morphological preservation, obscuring artefacts, immunocytochemistry (ICC), suitability for molecular analysis, and cost of preparation. Design: A total of 80 fine-needle aspirates from various sites and serous effusion samples were included. Of these cases, by random...

... Immunocytochemistry Molecular studies In pediatrics, the designation small blue cell tumors or more commonly small round cell tumors (SRCTs) are a generic term used to describe a heterogeneous group of pediatric malignant neoplasms, characterized for sharing the overlapping morphological pattern suggested...

...Satoshi Morito; Takao Nitanda; Ryuko Tsukamoto; Shingo Kamoshida; Hiroshi Yasui; Tomoo Itoh; Hiroyuki Ohsaki Immunocytochemistry (ICC) is an important ancillary technique in clinical cytology for not only identifying and characterizing tumor cells but also gaining prognostic or therapeutic...

...Katsuhide Ikeda; Shouichi Sato; Hiroshi Chigira; Yasuo Shibuki; Nobuyoshi Hiraoka Introduction: In effusion cytology, immunocytochemistry is a useful staining approach to provide important information for diagnosis. Effusion cytology is performed not only for pleural effusions and ascites but also...

.... Enhancer of zeste homolog 2 Immunocytochemistry Effusion cytology Reactive mesothelial cells Metastatic carcinoma Exfoliative cytological evaluation of effusion fluids is a simple, rapid, yet cost-effective means routinely used to detect exfoliated cancer cells. This technique is essential...

... will briefly review the main modern applications of FNAB of the breast when coupled with contemporary ancillary techniques. Such contemporary ancillary techniques range from classic immunocytochemistry (ICC) to the most modern molecular techniques, particularly next-generation sequencing. Coupled...

..., instructions or products referred to in the content or advertisements. Ancillary techniques Effusion cytology Immunocytochemistry Special stains, specifically histochemistry and immunohistochemistry (IHC), are valuable ancillary studies routinely used in fluid cytology. In general, cell block...

... brushing, fine needle aspiration, and pleural fluid) with different technical preclinical management protocols and different diagnostic yields. Immunocytochemistry (ICC) has a pivotal role in the determination of diagnostic, prognostic, and predictive markers. Therefore, limited cytology samples...

...: We evaluated the stability of immunocytochemistry (ICC) of ER and HER2 for primary or recurrent breast cancer samples rinsed in CP vials. Samples were prepared from CP vials stored for 1–30 or 160–240 days. ER and HER2 statuses were determined after 1–30 days (26 and 25 tests, respectively) or 160...