...Kosuke Inoue; Reiji Haba; Kana Kiyonaga; Toru Matsunaga; Seiko Kagawa; Toshitetsu Hayashi; Ryou Ishikawa Introduction: This study aimed to clarify the diagnostic structural features in cytology specimens that are useful in subtyping non-small cell lung carcinoma (NSCLC) into adenocarcinoma (ADC...

...Gunjan Mangla; Pooja Bakshi; Poojan Agarwal; Kusum Verma Introduction: Fluid cytology for malignant cells is important for diagnosis and staging of malignancies. Morphological overlap between reactive mesothelial cells and adenocarcinoma poses challenges, for which many immunohistochemical markers...

... (AGC) not otherwise specified, 4 cases of endocervical-type AGC and 4 cases favoring neoplastic-type AGC, 2 cases of adenocarcinoma of the endocervical type, 3 cases of adenocarcinoma of the endometrial type, and 1 case of extrauterine adenocarcinoma. Histopathological correlation was available in 12...

... adenocarcinoma cells (MAC) from reactive mesothelial cells (RMC) in effusions. Study Design: Claudin-3 and claudin-4 immunocytochemical staining was performed on 234 cell block specimens, including 194 malignant effusions with MAC and 40 benign effusions with RMC. Any degree of membranous staining was considered...

... method using Ber-EP4 that is applicable to intraoperative cancer cytodiagnosis. Results: The adenocarcinoma markers were positive in 92% of adenocarcinoma cases, 57% of cases with suspicion of adenocarcinoma, and 5% of negative cases (reactive mesothelial cells). On the other hand, the mesothelial cell...

...Kun Jiang; Diane Lawson; Cynthia Cohen; Momin T. Siddiqui Objective: Galectin-3 has been implicated in the carcinogenesis of pancreatic ductal adenocarcinoma (PDAC). Its applicability in pancreatic fine-needle aspiration (FNA) in separating malignant from benign lesions has never been addressed...

...Jin Seong Cho; Ga-Eon Kim; Ji Shin Lee; Jae Hyuk Lee; Jong Hee Nam; Chan Choi Objective: The aim of our study was to determine the diagnostic value of MUC1 and MUC4 for distinguishing between metastatic adenocarcinoma cells (MAC) and reactive mesothelial cells (RMC) in effusion fluids. Study Design...

...% of these cases represented ASqC. The other cases were contamination (52%) or atypical (<1%). ASqC constituted 4.5% (46/1,025) of all primary pancreatic exocrine malignancies. When compared with conventional adenocarcinoma, ASqC demonstrated a significantly poorer overall median survival (11.0 vs. 6.51 months...

..., correlated with histology and reevaluated using parameters based on architectural pattern, cellular features and background. Results: This study revealed 15 false positives. On review, 11 cases [1 adenocarcinoma, 5 atypical glandular cells (AGC), not otherwise specified, 5 AGC, favor neoplasia (FN)] were...

...Andre L. Moreira; Adnan Hasanovic The discovery of targetable driver mutations in pulmonary adenocarcinoma has revolutionized the field of thoracic oncology by the introduction of oral small molecule tyrosine kinase inhibitors that target specific EGFR mutations and EML-4/ALK rearrangement...

...), and adenocarcinoma (ADC) tissue was derived from miRNA expression studies and applied towards characterization of poorly differentiated NSCLC samples. Results: Microarray data from a genome-wide scan revealed 34 differentially expressed miRNAs, 5 of which enabled algorithmic discrimination of normal tissue from...

...Teresa S. Hyun; Michael Barnes; Z. Laura Tabatabai Objective: To evaluate the utility of the lymphatic endothelial marker D2-40, along with calretinin, CK5/6, desmin and MOC-31, in differentiating mesothelioma and adenocarcinoma in pleural effusion cytology. Study Design: Forty-five pleural...

... use of specimens for an accurate diagnosis and to preserve as much tissue as possible for potential molecular markers has been recommended. Study Design: In this study we blind-reviewed 50 cases of cytologically diagnosed non-small-cell type lung carcinomas and categorized them into adenocarcinoma...

...Hillary Z. Kimbrell; Karen S. Gustafson; Min Huang; Hormoz Ehya Objectives: To determine the diagnostic accuracy of cytomorphology for subclassifying non-small cell lung cancer into adenocarcinoma (AC) and squamous cell carcinoma (SqC), and the utility of immunocytochemistry (ICC) for poorly...

...Lian Liu; Cynthia Cohen; Momin T. Siddiqui Objective: Thyroid transcription factor 1 (TTF-1)/napsin A double staining is useful for the identification of primary lung adenocarcinoma. We examined its performance in pleural fluid. Study Design: Thirty-eight pleural-fluid specimens with lung...

...H. Nasser; T.J. Kuntzman Objectives: Pleural fluid metastasis occurs often secondary to a known primary tumor. We aim to identify the percentage of adenocarcinomas metastatic to pleural effusion in women and the frequency of another primary tumor being the origin of the effusion using morphology...

...Maria Drijkoningen; Beatrijs Meertens; Joseph Lauweryns cytodiagnosis cervix neoplasms neoplasms, squamous cell adenocarcinoma cervix uteri cervix dysplasia carcinoma in situ ; cytology 1996 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. mesothelioma adenocarcinoma immunohistochemistry Ber-EP4 30 9 2011 Acta Cytologica Ber-EP4 for Differentiating Adenocarcinoma from...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. adenocarcinoma cervix neoplasms cervix dysplasia Acta Cytologica Glandular Lesions of the Cervix Validity of Cytologic Criteria Used To Differentiate Reactive Changes...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. adenocarcinoma cervix neoplasms Acta Cytologica Cytologic Features of Well-Differentiated Villoglandular Adenocarcinoma of the Cervix Michael S...