..., instructions or products referred to in the content or advertisements. 2022 Human papillomavirus Conization Cervical cancer Screening Pre-cancer treatment Cervical cancer remains the fourth most common gynecologic malignancy worldwide, and its incidence continues to increase in Japan [ 1, 2...

... journey in the development of computer-assisted Pap test screening. Summary: The initial driving force for automated screening in cytology was the overwhelming number of Pap tests requiring manual screening, leading to workflow backlogs and incorrect diagnoses. Several companies invested resources...

...Bernhard Reinhold Mangold Objective: In order to increase overall participation in cervical cancer screening, several investigators propose a concept of introducing self-tests. The study presented here compared test results of the Pap test and 4 different HPV test systems of self-collected...

... significance (ASC-US) increased from 0.90% in 2004 to 2.47% in 2013 by routine screening. Detection of atypical squamous cells, cannot exclude a high-grade squamous intraepithelial lesion (ASC-H) increased from 13.33% in 2004 to 36.27% in 2013 by 100% RR. Detection of high-grade squamous intraepithelial lesion...

...Christine Bergeron; Magnus von Knebel Doeberitz Objectives: Cervical cancer screening test performance has been hampered by either a lack of sensitivity in Pap cytology or a lack of specificity of human papillomavirus (HPV) testing. This is disturbing for patients and a cause of high costs...

... at screening for microfollicular atypia. Methods: 8,814 thyroid FNA specimens were identified in our archives, all screened by 1 of 11 CTs and signed out by a cytopathologist. A subsample of cases was categorized either as atypia of uncertain significance (AUS) with microfollicular proliferation (AUS-F...

...Hiroyuki Kuramoto; Midori Banno; Masuko Hori; Jun Miyagawa; Manichi Iida; Miwa Kawaguchi Objective: To find an appropriate sampling device for a liquid-based procedure in the population screening for cervical cancer, focusing on bleeding at sampling and the amount of cells smeared. Methods...

...Setsu Akamatsu; Shoji Kodama; Yukari Himeji; Naomi Ikuta; Nikako Shimagaki Objective: To clarify the performance of liquid-based cytology (LBC) and conventional methods of preparing cervical specimens for cytological screening. Study Design: We studied 236,511 patients who participated...

... discontinuation of cervical cancer screening between 65 and 70 years of age in women with no abnormal test results in the preceding 10 years. This population-based study was undertaken to determine the incidence of cervical cancer in different age groups as a means to establish if current screening...

...Hiroyuki Kuramoto; Yoshiko Iwami; Naoko Sugimoto; Chizuyo Kato; Takashi Sugahara; Manichi Iida Objective: To evaluate the usefulness of a new liquid-based cytological procedure in a population screening program for cervix cancer. Subjects and Methods: Subjects were 1,000 women who underwent primary...

... and population-based tive infection. screening programs. b) Rarely, HPVs induce a proliferative epithelial phe- Consensus Position notype that pathologists recognize as a high grade lesion and that is the proximate cytohistologic precursor of in- 1. Based on the available molecular, clinical and epide- vasive...

... screened at Kaiser Permanente San Francisco (San Francisco, Calif., USA), 2 anal specimens were collected, 1 with each swab in random order, and placed into liquid cytology medium. Specimens were tested for cellularity by quantifying a genomic DNA (erv-3) . The number of cells was assessed from prepared...

... with the NPS. The performances of CC and NPS were evaluated for accuracy and compared using the gold standard of a combination of one of the two methods of pathological cytology with screening for positive human papilloma virus, quantification of cells (normal and pathological), and improvement in the quality...

... = 0.019), the HSIL (p < 0.000) and the IC (p < 0.000) group but not with the ASC-US (p = 0.342) group. Conclusions: MN scoring on the epithelial cells of cervix could be used as a biomarker in cancer screening. This is an easy, simple, reliable, reproducible and objective test which can be performed...