... is the most widely used predictive marker for immune checkpoint inhibitor (ICI) therapy in patients with lung adenocarcinoma. However, the current understanding of the association between PD-L1 expression and treatment response is suboptimal. A significant percentage of patients have only a cytological...

...Yang Ma; Jingxia Zhao; Yun Du; Rui Wang; Xiaokun Ji; Juan Wu; Xiao Guo; Ying Liu; Yan Zhang Objective: The aim of the study was to investigate the mutation status of multiple driver genes by RT-qPCR and their significance in advanced lung adenocarcinoma using cytological specimens. Materials...

... lung adenocarcinoma cells in BPE for more efficient RNA extraction and ALK gene detection. Materials and Methods: CEM proposed in this study and the traditional CSM and CBM were used to treat BPE samples collected from 37 lung adenocarcinoma patients. A DeNovix DS-11 ultraviolet spectrophotometer...

...Kevan J. Salimian; Roghayeh Fazeli; Gang Zheng; David Ettinger; Zahra Maleki Objectives: We analyzed the morphologic features and clinical characteristics of lung adenocarcinomas (ACAs) harboring mutated BRAF . Study Design: A review of the histology/cytology of BRAF -mutated lung ACAs...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Pleural effusions Molecular testing Lung adenocarcinoma Bronchial washing Fine-needle aspiration smears...

... be really deceptive. A papillary pattern could cause problems in differentiation from a well-differentiated lung adenocarcinoma, particularly the lepidic type, a papillary thyroid carcinoma and a mesothelioma, but the morphology of the nuclei is straightforward. Round cells and typical papillary areas can...

...Sinchita Roy Chowdhuri; Jeffrey Hanson; Jerome Cheng; Jaime Rodriguez-Canales; Patricia Fetsch; Ulysses Balis; Armando C. Filie; Giuseppe Giaccone; Michael R. Emmert-Buck; Jason D. Hipp Objective: In the past decade molecular diagnostics has changed the clinical management of lung adenocarcinoma...