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1-20 of 71
Keywords: Liquid-based cytology
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Journal Articles
Subject Area:
Pathology and Cell Biology
Journal:
Acta Cytologica
Acta Cytologica (2025) 69 (3): 259–268.
Published Online: 11 March 2025
...Yukiko Matsuo; Tsutomu Yoshida; Kazuya Yamashita; Yukitoshi Satoh Introduction: Liquid-based cytology (LBC) specimens of lung cancer are increasingly being used for genetic analyses. Preservation conditions of specimens until DNA extraction are important because they can affect DNA quality. We...
Journal Articles
Subject Area:
Pathology and Cell Biology
Yoshiki Naito, Akihiko Kawahara, Ryo Makino, Takako Tokumitsu, Daisuke Nagayama, Eiji Sadashima, Kaori Nakamura, Ryoji Nishizaki, Tadasuke Nagatomo, Yukina Fujino, Chie Hayakawa, Keishi Mizuguchi, Tatsuya Mori, Kenichi Hirabayashi, Takuma Tajiri
Journal:
Acta Cytologica
Acta Cytologica (2025) 69 (3): 269–279.
Published Online: 28 February 2025
...Yoshiki Naito; Akihiko Kawahara; Ryo Makino; Takako Tokumitsu; Daisuke Nagayama; Eiji Sadashima; Kaori Nakamura; Ryoji Nishizaki; Tadasuke Nagatomo; Yukina Fujino; Chie Hayakawa; Keishi Mizuguchi; Tatsuya Mori; Kenichi Hirabayashi; Takuma Tajiri Introduction: The use of liquid-based cytology (LBC...
Journal Articles
Utility of p16INK4a Staining on Cell Blocks Prepared from Residual Liquid-Based Cervicovaginal Material
Available to PurchaseSubject Area:
Pathology and Cell Biology
Journal:
Acta Cytologica
Acta Cytologica (2025) 69 (3): 248–258.
Published Online: 10 February 2025
...Shabana Andleeb Ansari; Anshu Introduction: Cervical cancer screening using Pap smears is affected by false-negative results. Liquid-based cytology (LBC) offers the technical advantage of preparing cell blocks from residual fluid to conduct ancillary tests on them. The p16INK4a gene product has...
Journal Articles
Subject Area:
Pathology and Cell Biology
Maria Samara, Eleni Thodou, Christina Apostolopoulou, Panagiotis J. Vlachostergios, Lampros Mitrakas, Ioannis Zachos, Maria Anagnostou, George Koukoulis, Vassilios Tzortzis
Journal:
Acta Cytologica
Acta Cytologica (2024) 68 (6): 532–543.
Published Online: 23 September 2024
...) and telomerase reverse transcriptase (TERT) genes, in urine processed with liquid-based cytology (LBC) could enhance the diagnostic performance of cytology, particularly in defining the indeterminate categories of AUC and SHGUC. Methods: Urine samples from 82 UC patients with primary tumors or under surveillance...
Journal Articles
Quality Assurance in Immunocytochemistry: A Review and Practical Considerations
Available to PurchaseSubject Area:
Pathology and Cell Biology
Journal:
Acta Cytologica
Acta Cytologica (2025) 69 (1): 60–68.
Published Online: 24 July 2024
[email protected] Cytological samples Immunocytochemistry Cell block Liquid-based cytology Cytological smears Validation protocols References 1. Metovic J , Righi L , Delsedime L , Volante M , Papotti M . Role of immunocytochemistry in the cytological diagnosis...
Journal Articles
Subject Area:
Pathology and Cell Biology
Journal:
Acta Cytologica
Acta Cytologica (2025) 69 (1): 7–15.
Published Online: 22 July 2024
... diagnostic techniques have been applied, including immunocytochemistry (ICC). This review discusses the application and evaluation of ICC in thyroid fine needle aspiration. Summary: Currently, three immunostaining preparation methods are available for cytological materials: liquid-based cytology, cell block...
Journal Articles
Using the DNA Integrity Number to Analyze DNA Quality in Specimens Collected from Liquid-Based Cytology after Fine-Needle Aspiration of Breast Tumors and Lesions
Available to PurchaseSubject Area:
Pathology and Cell Biology
Akiyoshi Hoshino, Yoshiyasu Oana, Yasuyo Ohi, Yukari Maeda, Masako Omori, Yuki Takada, Tadashi Ikeda, Keiichi Sotome, Hinako Maeda, Takako Yanagisawa, Osamu Takeuchi, Satoshi Kuronuma, Takafumi Sangai, Yukiko Shibahara, Yoshiki Murakumo, Makoto Saegusa, Naoki Kanomata, Satoi Nagasawa, Rin Yamaguchi, Masayuki Yoshida, Yuji Kozuka, Hiroshi Matsumoto, Koichiro Tsugawa, Ichiro Maeda, Accuracy of Breast Fine-Needle Aspiration Cytology of the Japanese Society of Clinical Cytology
Journal:
Acta Cytologica
Acta Cytologica (2024) 68 (2): 145–152.
Published Online: 29 March 2024
... analyses were conventionally performed using formalin-fixed paraffin-embedded sections rather than cytology samples such as cell block or smear specimens. Specimens collected from liquid-based cytology (LBC) have the potential to be sources of high-quality DNA suitable for genetic analysis even after long...
Journal Articles
Can Endometrial Cytology Identify Patients Who Would Benefit from Immunotherapy?
Available to PurchaseSubject Area:
Pathology and Cell Biology
Shintaro Yanazume, Yukari Kirita, Yusuke Kobayashi, Ikumi Kitazono, Toshiaki Akahane, Mika Mizuno, Shinichi Togami, Akihide Tanimoto, Hiroaki Kobayashi
Journal:
Acta Cytologica
Acta Cytologica (2024) 68 (2): 128–136.
Published Online: 12 March 2024
...: 0.57–0.84), with a cutoff value of 26 high-power field. Conclusion: Lymphocyte count using liquid-based cytology for patients with endometrial cancer may predict POLE mut plus MMR-d of TCGA groups and TMB-high in those who can benefit from immunotherapy. [email protected]...
Journal Articles
Histopathologic Follow-Up of Women with Inadequate ThinPrep™ Cervical Pap Tests and Positive High-Risk Human Papillomavirus Test Results
Available to Purchase
Journal:
Acta Cytologica
Acta Cytologica (2023) 67 (5): 533–538.
Published Online: 26 July 2023
... results of cases with an unsatisfactory ThinPrep Pap test and positive hrHPV results were revealed. Methods: Between January 1, 2018, and October 31, 2022, 965 (3.7%) of 25,958 liquid-based cytology specimens were evaluated as unsatisfactory. Ninety-five (9.8%) of 965 patients were positive for hrHPV...
Journal Articles
Immunocytochemical Reactivity Comparison between Formalin-Fixed and Liquid-Based Cytology-Fixed Specimens
Available to PurchaseNanako Sakabe, Sayumi Maruyama, Chihiro Ito, Yuka Shimoyama, Tetsuya Komene, Wataru Oboshi, Shouichi Sato, Kazuhisa Sudo, Katsuhide Ikeda
Journal:
Acta Cytologica
Acta Cytologica (2023) 67 (1): 38–45.
Published Online: 24 January 2023
...Nanako Sakabe; Sayumi Maruyama; Chihiro Ito; Yuka Shimoyama; Tetsuya Komene; Wataru Oboshi; Shouichi Sato; Kazuhisa Sudo; Katsuhide Ikeda Introduction: Liquid-based cytology (LBC)-fixed samples can be used for preparing multiple specimens of the same quality and for immunocytochemistry (ICC...
Journal Articles
Diagnostic Performance of the Newly Developed WellPrep® Liquid-Based Cytology System and Its Comparison with SurePath TM in Cervical Squamous Lesions
Available to Purchase
Journal:
Acta Cytologica
Acta Cytologica (2023) 67 (1): 27–37.
Published Online: 24 January 2023
...Ji Eun Choi; Min-Sun Jin; Ilias P. Nikas; Han Suk Ryu Introduction: WellPrep® (WP), a fully automated, one-step liquid-based cytology (LBC) platform using an all-in-one closed chamber, has recently been developed as a next-generation LBC technology. This study aimed to evaluate the diagnostic...
Journal Articles
Morphometrical Differences among Endometrial Endometrioid Carcinoma Grade 1, Grade 3, and Serous Carcinoma in Endometrial Liquid-Based Cytology Preparations
Available to PurchaseSubject Area:
Pathology and Cell Biology
Hirokazu Odashima, Haruhiko Yoshioka, Kouki Minami, Keita Miyakawa, Kayo Horie, Yoshiaki Norimatsu, Kenji Yanoh, Jun Watanabe
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (6): 524–531.
Published Online: 12 September 2022
... with the conventional preparation can be dissolved by liquid-based cytology (LBC) preparation. The Yokohama System is a method for reporting endometrial cytology, but the system lumps cancers together and does not distinguish between histological types. The objective of this study was to clarify morphometrical...
Journal Articles
Relationship between Liquid-Based Cytology Preservative Solutions and Artificial Intelligence: Liquid-Based Cytology Specimen Cell Detection Using YOLOv5 Deep Convolutional Neural Network
Available to PurchaseSubject Area:
Pathology and Cell Biology
Katsuhide Ikeda, Nanako Sakabe, Sayumi Maruyama, Chihiro Ito, Yuka Shimoyama, Shouichi Sato, Kohzo Nagata
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (6): 542–550.
Published Online: 06 September 2022
... and developed in the field of cytopathology. Liquid-based cytology (LBC) enables standardized cytological preparation and is also applied to artificial intelligence (AI) research, but cytological features differ depending on the LBC preservative solution types. In this study, the relationship between cell...
Journal Articles
Effects of Menstrual Cycle on Various Morphologies of High-Grade Squamous Intraepithelial Lesions in SurePath™ Liquid-Based Cervical Cytology
Available to PurchaseSubject Area:
Pathology and Cell Biology
Mitsuaki Okodo, Kaori Okayama, Natsuko Tsukakoshi, Yukimi Misawa, Kazumasa Tanabe, Koji Teruya, Chieko Ito, Yasuyoshi Ishii, Masahiko Fujii, Mizue Oda
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (6): 507–512.
Published Online: 14 June 2022
... in the cytological triage of human papillomavirus-positive women. Methods: A total of 147 HSIL samples of liquid-based cytology (LBC) in patients with cervical intraepithelial neoplasia grade 2 or 3 were obtained, and then, the relationship between cellular patterns, such as single-cell-like and syncytial aggregates...
Journal Articles
Optimal Preservations of Cytological Materials Using Liquid-Based Cytology Fixatives for Next-Generation Sequencing Analysis
Available to PurchaseSubject Area:
Pathology and Cell Biology
Ryota Tanaka, Masachika Fujiwara, Yoko Nakazato, Nobuaki Arai, Keisei Tachibana, Norihiko Sakamoto, Koji Kishimoto, Hiroshi Kamma, Junji Shibahara, Haruhiko Kondo
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (5): 457–465.
Published Online: 12 April 2022
... need for molecular testing on cytology specimens. The aim of this study was to determine the optimal preservation methods of liquid-based cytology (LBC) materials for molecular testing. Methods: Cytological samples from 35 surgical resected non-small cell lung carcinoma specimens were obtained between...
Journal Articles
Subject Area:
Pathology and Cell Biology
Junichi Sakane, Hirotsugu Kitayama, Takashi Inoue, Akihiro Nakamura, Masayoshi Yamada, Yudai Miyama, Hideki Kawamura, Hideto Iwafuchi, Shingo Kamoshida, Hiroyuki Ohsaki
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (5): 434–440.
Published Online: 29 March 2022
...) immunoenzyme staining combined with liquid-based cytology can serve as a noninvasive routine laboratory test for glomerular disease. Methods: The presence of PDX- and WT1-positive cells was investigated in 79 patients with glomerular disease and 51 patients with nonglomerular disease. Results: The frequencies...
Journal Articles
Guided Needle Aspirations of Intra-Abdominal Masses: Analogy between Liquid-Based and Conventional Smear Preparation Methods
Available to PurchaseSubject Area:
Pathology and Cell Biology
Rinki Agrahari, Preeti Agarwal, Shalini Bhalla, Akshya Anand, Naseem Akhtar, Anit Parihar, Abhinav Arun Sonkar, Madhu Mati Goel
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (3): 197–205.
Published Online: 04 March 2022
... false negatives due to faulty smear preparations. Liquid-based cytology (LBC) can be advantageous in these scenarios. Hence, with an aim to investigate utility of LBC in these samples, we carried out the above study with objectives to find diagnostic accuracy of LBC and agreement of LBC with CS methods...
Journal Articles
Comparison of Morphological Similarities and Differences between Liquid-Based Cytology and Conventional Techniques of Serous Effusion Cytology Specimens
Available to PurchaseSubject Area:
Pathology and Cell Biology
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (2): 159–164.
Published Online: 30 December 2021
.... Cytopreparations Liquid-based cytology Serous effusions Serous effusions are peritoneal, pleural, pericardial fluids and intraoperative peritoneal washing fluids [1]. Normally, these cavities are collapsed and contain a small amount of fluid that enables the superimposed motion of the adjacent surfaces...
Journal Articles
Concordance of Cytological Specimens with Histological Tissue for Detection of Epidermal Growth Factor Receptor Mutation in Non-Small Cell Lung Cancer: A Systematic Review
Available to PurchaseSubject Area:
Pathology and Cell Biology
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (1): 61–71.
Published Online: 27 October 2021
...Tzy Harn Chua; Khoon Leong Chuah Introduction: There is increasing need for more testing in non-small cell lung cancer given the introduction of newer targeted therapies. Cytological specimens including conventional smears (CS), cell blocks (CB), and liquid-based cytology (LBC) are an alternative...
Journal Articles
Characterizing the Effect of Processing Technique and Solution Type on Cytomorphology Using Liquid-Based Cytology
Available to PurchaseSubject Area:
Pathology and Cell Biology
Katsuhide Ikeda, Wataru Oboshi, Yusuke Hashimoto, Tetsuya Komene, Yoshitaka Yamaguchi, Shouichi Sato, Sayumi Maruyama, Nozomi Furukawa, Nanako Sakabe, Kohzo Nagata
Journal:
Acta Cytologica
Acta Cytologica (2022) 66 (1): 55–60.
Published Online: 13 October 2021
...Katsuhide Ikeda; Wataru Oboshi; Yusuke Hashimoto; Tetsuya Komene; Yoshitaka Yamaguchi; Shouichi Sato; Sayumi Maruyama; Nozomi Furukawa; Nanako Sakabe; Kohzo Nagata Introduction: Liquid-based cytology (LBC) is increasingly used for nongynecologic applications. However, the cytological preparation...
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