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Keywords: Cell blockClose
Sarah A. Anderson, Djamel Harbi, Diana Oramas Mogrovejo, Antoinette D. Floyd, Isam-Eldin Eltoum, Huma Fatima, Frida Rosenblum, Manuel Lora Gonzalez, Diana Lin, Alexander C. Mackinnon, Gene P. Siegal, Thomas Winokur, Ceren Yalniz, Lei Huo, Shuko Harada, Xiao Huang
Acta Cytologica 1–12.
Published Online: 26 July 2023
... targeted next-generation sequencing analysis and paired PD-L1 (22C3) immunohistochemical staining performed on the same cell blocks. We explored the association between molecular features and PD-L1 expression. In patients who underwent ICIs therapy, we assessed how a specific gene mutation impacted...
Nanako Sakabe, Sayumi Maruyama, Chihiro Ito, Yuka Shimoyama, Tetsuya Komene, Wataru Oboshi, Shouichi Sato, Kazuhisa Sudo, Katsuhide Ikeda
Acta Cytologica (2023) 67 (1): 38–45.
Published Online: 24 January 2023
...); however, LBC fixing solutions affect immunoreactivity. Therefore, in this study, we examined the effect of LBC fixing solutions on immunoreactivity. Methods: Samples were cell lines, and specimens were prepared from cell blocks of 10% neutral buffered formalin (NBF)-fixed samples and the four types of LBC...
Ryota Tanaka, Masachika Fujiwara, Yoko Nakazato, Nobuaki Arai, Keisei Tachibana, Norihiko Sakamoto, Koji Kishimoto, Hiroshi Kamma, Junji Shibahara, Haruhiko Kondo
Acta Cytologica (2022) 66 (5): 457–465.
Published Online: 12 April 2022
... centrifugation), and LBC-Cell Block (LBC-CB) group (generation of paraffin-embedded CB and storage at 4°C). Samples from 5 patients were used for the time course analysis, and we performed evaluations on these samples at 1, 3, 6, 12, 24, and 36 months. The concentrations and purities of extracted DNA and RNA...
Acta Cytologica (2022) 66 (1): 14–22.
Published Online: 17 November 2021
... molecular subtypes by using immunohistochemistry (IHC). Fine-needle aspiration biopsy cytology (FNABC) is a first-line diagnostic modality in lymphadenopathy. The study aims to perform IHC on FNABC cell blocks (CBs) for subclassifying according to the Hans algorithm and correlate with case-matched...
Acta Cytologica (2022) 66 (1): 72–78.
Published Online: 29 October 2021
...Shruti Gupta; Upasana Gautam; Shaily Susheilia; Baneet Bansal; Radha Uppal; Radhika Srinivasan Background: Cell blocks (CBs) are an essential adjunct in cytopathology practice. The aim of this study was to compare 2 techniques of CB preparation – plasma thrombin (PT) method with sodium alginate (SA...
Acta Cytologica (2021) 65 (5): 361–367.
Published Online: 08 July 2021
...Kaveri Hallikeri; Biji Babu; Archana Sudhakaran; Roshni Monteiro Objectives: To determine the role and efficacy of fine needle aspiration cytology (FNAC) and cell block in diagnosis of jaw lesions and compare the agreement between FNAC and cell block to predict the diagnosis. Method: The sample...
Mohammed S.I. Mansour, Kajsa Ericson Lindquist, Tomas Seidal, Ulrich Mager, Rikard Mohlin, Lena Tran, Kim Hejny, Benjamin Holmgren, Despoina Violidaki, Katalin Dobra, Annika Dejmek, Maria Planck, Hans Brunnström
Acta Cytologica (2021) 65 (6): 501–509.
Published Online: 07 July 2021
..., instructions or products referred to in the content or advertisements. 22C3 28-8 Cell block Cytology CytoLyt Histology PreservCyt In non-small cell lung cancer (NSCLC), immunohistochemical (IHC) staining for programmed death-ligand 1 (PD-L1) is used to predict response to immune checkpoint...
Acta Cytologica (2021) 65 (3): 257–263.
Published Online: 31 March 2021
...Mikk Abram; Roope Huhtamella; David Kalfert; Heli Hakso-Mäkinen; Marie Ludvíková; Ivana Kholová Introduction: Thyroid cytology is a widely accepted tool in the clinical triaging of nodular lesions. Cell blocks (CBs) can help in the diagnosis of atypical lesions, namely, thyroid Bethesda category...
Acta Cytologica (2020) 64 (5): 507–510.
Published Online: 06 April 2020
... in the pathology department for evaluation. Two-hundred milliliters of red-colored pericardial fluid (PF) were harbored , centrifuged, and both conventional and Cytotec smears were prepared and stained with field and pap stain. In addition, a cell block was made for analysis. What is your diagnosis...
Acta Cytologica (2020) 64 (3): 265–269.
Published Online: 30 August 2019
...Heli Hakso-Mäkinen; Ivana Kholová Objective: Cell blocks (CBs) are used to complement cytological diagnosis and for ancillary testing. Dissatisfaction with the cellular yield of the CB is widely recognized. Various techniques have been developed to increase the diagnostic utility of CBs. Study...
Acta Cytologica (2020) 64 (3): 256–264.
Published Online: 29 August 2019
... mesothelial cells. The use of ancillary tools can reduce this grey zone and help to achieve a definitive diagnosis. Objectives: The main objective of this study was to evaluate the role of flow cytometry (FCM) and cell block with immunohistochemistry (IHC), along with the clinicoradiological investigations...
Acta Cytologica (2020) 64 (1-2): 16–29.
Published Online: 15 March 2019
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cell block Diagnostic cytology Immunocytochemistry Lung cancer Predictive markers...
Acta Cytologica (2019) 63 (1): 63–72.
Published Online: 09 January 2019
...Zeinab Amiri; Mozhdeh Momtahan; Maral Mokhtari Background: Peritoneal washing cytology has become an accepted method in evaluating gynecology malignancies. Objective: The aim of this work was to compare the conventional cytology, liquid-based cytology (LBC), and cell block in the evaluation...
Acta Cytologica (2019) 63 (1): 28–34.
Published Online: 04 January 2019
... of scraping material from cytological smears to manufacture cell blocks to provide material for ancillary studies. Our objective was a retrospective review of the PathWest (QE2) experience with manufactured cell blocks (mCB) over the last 10 years. A total of 178 fine-needle aspiration cases with mCB were...
Acta Cytologica (2018) 62 (4): 237–243.
Published Online: 15 June 2018
...Leena Krogerus; Ivana Kholová Objective: The cell block (CB) technique refers to the processing of sediments, blood clots, or grossly visible tissue fragments from cytological specimens into paraffin blocks that can be cut and stained by the same methods used for histopathology. The technique...
Rieko Nishimura, Yuya Murata, Kiyoshi Mori, Katsushige Yamashiro, Kazuya Kuraoka, Shu Ichihara, Kenichi Taguchi, Hiroyoshi Suzuki, Masahiro Ito, Natsumi Yamashita
Acta Cytologica (2018) 62 (4): 288–294.
Published Online: 15 May 2018
...Rieko Nishimura; Yuya Murata; Kiyoshi Mori; Katsushige Yamashiro; Kazuya Kuraoka; Shu Ichihara; Kenichi Taguchi; Hiroyoshi Suzuki; Masahiro Ito; Natsumi Yamashita Objective: We explore the problems associated with the cell block (CB) method for receptor analysis in breast cancer metastases...
Niki Margari, Ilias Giovannopoulos, Abraham Pouliakis, Emmanouil Mastorakis, Alina Roxani Gouloumi, Ioannis G. Panayiotides, Petros Karakitsos
Acta Cytologica (2018) 62 (2): 137–144.
Published Online: 16 January 2018
...Niki Margari; Ilias Giovannopoulos; Abraham Pouliakis; Emmanouil Mastorakis; Alina Roxani Gouloumi; Ioannis G. Panayiotides; Petros Karakitsos Objective: To investigate the potential of Classification and Regression Trees (CARTs) for the diagnosis of thyroid lesions based on cell block...
Acta Cytologica (2018) 62 (1): 39–43.
Published Online: 15 November 2017
...Karishma M. Desai; Punnya V. Angadi; Alka D. Kale; Seema Hallikerimath Objectives: Cell block preparation is a recognized technique in histopathological diagnosis. This technique aids in maintaining an intact architecture and reducing the diagnostic errors associated with fine-needle aspiration...
Acta Cytologica (2017) 61 (1): 17–20.
Published Online: 24 November 2016
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Head and neck neoplasms Fine-needle biopsy Fine-needle aspirate Immunohistochemistry Histo-fragment Histo-block Cell block Salivary gland Tumours...
Acta Cytologica (2016) 60 (1): 74–78.
Published Online: 27 February 2016
... washings (BTW) and evaluate the feasibility of IHC testing on these samples. Study Design: All patients who had cell blocks (CB) created from BTW following bronchoscopic investigation of peripheral lung lesions were included. CB were assessed for adequate material before undergoing IHC staining. Results...