... from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Cytological samples Immunocytochemistry Cell block Liquid-based cytology Cytological smears Validation protocols Cytological samples are often the only material available...

... to reduce atypical cases and improve diagnostic accuracy by investigating the utility of cell block (CB) analysis. Methods: FNAB CB samples (2018–2022) were reviewed using smear only or CBs. CB-based diagnosis was performed with 2D morphological analysis and immunocytochemistry using ER, CK5/6, p63, SMA...

... targeted next-generation sequencing analysis and paired PD-L1 (22C3) immunohistochemical staining performed on the same cell blocks. We explored the association between molecular features and PD-L1 expression. In patients who underwent ICIs therapy, we assessed how a specific gene mutation impacted...

...); however, LBC fixing solutions affect immunoreactivity. Therefore, in this study, we examined the effect of LBC fixing solutions on immunoreactivity. Methods: Samples were cell lines, and specimens were prepared from cell blocks of 10% neutral buffered formalin (NBF)-fixed samples and the four types of LBC...

... centrifugation), and LBC-Cell Block (LBC-CB) group (generation of paraffin-embedded CB and storage at 4°C). Samples from 5 patients were used for the time course analysis, and we performed evaluations on these samples at 1, 3, 6, 12, 24, and 36 months. The concentrations and purities of extracted DNA and RNA...

... molecular subtypes by using immunohistochemistry (IHC). Fine-needle aspiration biopsy cytology (FNABC) is a first-line diagnostic modality in lymphadenopathy. The study aims to perform IHC on FNABC cell blocks (CBs) for subclassifying according to the Hans algorithm and correlate with case-matched...

...Shruti Gupta; Upasana Gautam; Shaily Susheilia; Baneet Bansal; Radha Uppal; Radhika Srinivasan Background: Cell blocks (CBs) are an essential adjunct in cytopathology practice. The aim of this study was to compare 2 techniques of CB preparation – plasma thrombin (PT) method with sodium alginate (SA...

...Kaveri Hallikeri; Biji Babu; Archana Sudhakaran; Roshni Monteiro Objectives: To determine the role and efficacy of fine needle aspiration cytology (FNAC) and cell block in diagnosis of jaw lesions and compare the agreement between FNAC and cell block to predict the diagnosis. Method: The sample...

..., instructions or products referred to in the content or advertisements. 22C3 28-8 Cell block Cytology CytoLyt Histology PreservCyt In non-small cell lung cancer (NSCLC), immunohistochemical (IHC) staining for programmed death-ligand 1 (PD-L1) is used to predict response to immune checkpoint...

...Mikk Abram; Roope Huhtamella; David Kalfert; Heli Hakso-Mäkinen; Marie Ludvíková; Ivana Kholová Introduction: Thyroid cytology is a widely accepted tool in the clinical triaging of nodular lesions. Cell blocks (CBs) can help in the diagnosis of atypical lesions, namely, thyroid Bethesda category...

... in the pathology department for evaluation. Two-hundred milliliters of red-colored pericardial fluid (PF) were harbored , centrifuged, and both conventional and Cytotec smears were prepared and stained with field and pap stain. In addition, a cell block was made for analysis. What is your diagnosis...

...Heli Hakso-Mäkinen; Ivana Kholová Objective: Cell blocks (CBs) are used to complement cytological diagnosis and for ancillary testing. Dissatisfaction with the cellular yield of the CB is widely recognized. Various techniques have been developed to increase the diagnostic utility of CBs. Study...

... mesothelial cells. The use of ancillary tools can reduce this grey zone and help to achieve a definitive diagnosis. Objectives: The main objective of this study was to evaluate the role of flow cytometry (FCM) and cell block with immunohistochemistry (IHC), along with the clinicoradiological investigations...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cell block Diagnostic cytology Immunocytochemistry Lung cancer Predictive markers...

...Zeinab Amiri; Mozhdeh Momtahan; Maral Mokhtari Background: Peritoneal washing cytology has become an accepted method in evaluating gynecology malignancies. Objective: The aim of this work was to compare the conventional cytology, liquid-based cytology (LBC), and cell block in the evaluation...

... of scraping material from cytological smears to manufacture cell blocks to provide material for ancillary studies. Our objective was a retrospective review of the PathWest (QE2) experience with manufactured cell blocks (mCB) over the last 10 years. A total of 178 fine-needle aspiration cases with mCB were...

...Leena Krogerus; Ivana Kholová Objective: The cell block (CB) technique refers to the processing of sediments, blood clots, or grossly visible tissue fragments from cytological specimens into paraffin blocks that can be cut and stained by the same methods used for histopathology. The technique...

...Rieko Nishimura; Yuya Murata; Kiyoshi Mori; Katsushige Yamashiro; Kazuya Kuraoka; Shu Ichihara; Kenichi Taguchi; Hiroyoshi Suzuki; Masahiro Ito; Natsumi Yamashita Objective: We explore the problems associated with the cell block (CB) method for receptor analysis in breast cancer metastases...

...Niki Margari; Ilias Giovannopoulos; Abraham Pouliakis; Emmanouil Mastorakis; Alina Roxani Gouloumi; Ioannis G. Panayiotides; Petros Karakitsos Objective: To investigate the potential of Classification and Regression Trees (CARTs) for the diagnosis of thyroid lesions based on cell block...

...Karishma M. Desai; Punnya V. Angadi; Alka D. Kale; Seema Hallikerimath Objectives: Cell block preparation is a recognized technique in histopathological diagnosis. This technique aids in maintaining an intact architecture and reducing the diagnostic errors associated with fine-needle aspiration...