Sympathetic supply to the saphenous and dorsal pedal arteries of canine hindlimbs was determined using the glyoxylic acid method for monoamines for the fluorescence histochemical demonstration. Adrenergic nerve fibers of the dorsal pedal artery had almost completely disappeared after L6, L7 sympathectomy. The fibers of the saphenous artery had disappeared by about 90% by L3–L5 sympathectomy. It is concluded that all the postganglionic fibers distributed to the dorsal pedal artery originate in L6 and L7 ganglia and 90% of those distributed to the saphenous artery originate in L3–L5 ganglia.

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