The mechanically induced rabbit hydrosalpinx, a frequently studied animal model of human hydrosalpinges, was examined to determine the variations, in vascular perfusion and capillary albumin permeability, which occur in hydrosalpinges. At laparotomy, 4 adult female virgin rabbits underwent isthmic and ampullary occlusion with small tantalum clips. 4 weeks later, fluorescein isothiocyanate-labelled bovine serum albumin (FITC BSA: molecular weight 67,000) was injected intravenously 5 min before oviduct excision. Examination of tubal sections by incident light fluorescent microscopy demonstrated poor interplical vascular perfusabüity and markedly reduced interplical capillary permeability to FITC BSA in both isthmic and ampullary segments of hydrosalpinx. These observations imply that, in the experimental rabbit hydrosalpinx, interplical deciliation is probably vascular in origin; furthermore the marked decrease in capillary macromolecule permeability may explain the serous fluid collection within the hydrosalpinx. Poor fecundity following microsurgical restoration of tubal patency in hydrosalpinges is possibly due to the failure of this decrease in submucosal capillary perfusabüity and macromolecular permeability to resolve.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.